IL29 Protein (AA 1-200)

Produktnummer ABIN7505594

Dieses Recombinant IL29-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für IL29 Protein (AA 1-200) (ABIN7505594)

Target: IL29 (Interleukin 29 (IL29))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-200

Sequenz: Met1-Thr200

Produktmerkmale: A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IL29 (Interleukin 29 (IL29))

Andere Bezeichnung: IL-29

Hintergrund:

Abbreviation: IL-29

Target Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21

Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Molekulargewicht:

Calculated MW: 22 kDa

Observed MW: 28-35 kDa

UniProt: Q8IU54