MUC16 Protein (AA 6188-6372) (His tag)

Produktnummer ABIN7505452

Dieses Recombinant MUC16-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für MUC16 Protein (AA 6188-6372) (His tag) (ABIN7505452)

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 6188-6372

Aufreinigungstag / Konjugat: Dieses MUC16 Protein ist gelabelt mit His tag.

Sequenz: Ile 6188-Ser 6372

Produktmerkmale: A DNA sequence encoding the Mouse MUC16 protein (A0A140LJ72) (Ile 6188-Ser 6372) was expressed with N-His tag.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Andere Bezeichnung: MUC16

Hintergrund:

Abbreviation: MUC16

Target Synonym: Mucin 16,Muc16

Background: Mucin-16 is a heavily O-glycosylated protein that can be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus, which induces proteolytic cleavage and liberation of extracellular domain. I provides protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Mucin-16 is composed of three domains: a Serine, Threonine-rich N-terminal domain, a repeated domain containing between 12 and 60 partially conserved tandem repeats of 156 amino acids and a C-terminal transmembrane domain with a short cytoplasmic tail.

Molekulargewicht:

Calculated MW: 20.24 kDa

Observed MW: 25 kDa

UniProt: A0A140LJ72