Annexin a1 Protein (AA 2-346)

Produktnummer ABIN7504971

Recombinant Annexin a1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Annexin a1 Protein (AA 2-346) (ABIN7504971)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 2-346

Sequenz: Ala 2-Asn 346

Produktmerkmale: Recombinant Human Annexin A1 is produced by our E.coli expression system and the target gene encoding Ala2-Asn346 is expressed.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: Annexin A1

Hintergrund:

Abbreviation: Annexin A1,ANXA1

Target Synonym: Annexin A1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 Inhibitory Protein,p35

Background: Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97 % of samples from patients with hairy cell leukemia.

Molekulargewicht:

Calculated MW: 38.6 kDa

Observed MW: 34 kDa

UniProt: P04083

Pathways: Hormone Transport