NKG2A & CD94 protein (mFc Tag)

Produktnummer ABIN7488870

Dieses Recombinant -Protein wird in HEK-293 Cells produziert.

Kurzübersicht für NKG2A & CD94 protein (mFc Tag) (ABIN7488870)

Target: NKG2A & CD94

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Reinheit: 95 %

Güteklasse: MALS verified

Produktdetails

Aufreinigungstag / Konjugat: mFc Tag

Verwendungszweck: Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)

Sequenz: Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94)

Produktmerkmale: Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1(NKG2A) & O35778-1(CD94).

Endotoxin-Niveau: 1.0 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: NKG2A & CD94

Andere Bezeichnung: NKG2A&CD94

Hintergrund: CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Molekulargewicht: 61.0 kDa