LTA Protein (His tag)
Kurzübersicht für LTA Protein (His tag) (ABIN7488960)
Target
Alle LTA Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
Güteklasse
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Aufreinigungstag / Konjugat
- Dieses LTA Protein ist gelabelt mit His tag.
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Verwendungszweck
- Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified)
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Sequenz
- Leu 35 - Leu 205
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Produktmerkmale
- Human TNF-beta Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 35 - Leu 205 (Accession # P01374).
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Endotoxin-Niveau
- 1.0 EU per μg
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Kommentare
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 20.5 kDa. The protein migrates as 26-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- LTA (Lymphotoxin-alpha (LTA))
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Andere Bezeichnung
- TNF-beta
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Substanzklasse
- Chemical
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Hintergrund
- The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.
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Molekulargewicht
- 20.5 kDa
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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