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LTA Protein (His tag)

Dieses Recombinant LTA-Protein wird in HEK-293 Cells exprimiert.
Produktnummer ABIN7488960

Kurzübersicht für LTA Protein (His tag) (ABIN7488960)

Target

Alle LTA Proteine anzeigen
LTA (Lymphotoxin-alpha (LTA))

Protein-Typ

Recombinant

Spezies

  • 9
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 23
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Reinheit

90 %

Güteklasse

MALS verified
  • Aufreinigungstag / Konjugat

    Dieses LTA Protein ist gelabelt mit His tag.

    Verwendungszweck

    Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified)

    Sequenz

    Leu 35 - Leu 205

    Produktmerkmale

    Human TNF-beta Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 35 - Leu 205 (Accession # P01374).

    Endotoxin-Niveau

    1.0 EU per μg
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  • Kommentare

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 20.5 kDa. The protein migrates as 26-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C
  • Target

    LTA (Lymphotoxin-alpha (LTA))

    Andere Bezeichnung

    TNF-beta

    Substanzklasse

    Chemical

    Hintergrund

    The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

    Molekulargewicht

    20.5 kDa

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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