tau-441 (Active) Protein

Produktnummer ABIN7488816

Produktdetails

Target: tau-441

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active)

Sequenz: Met 1 - Leu 441

Produktmerkmale: Human Tau-441 Pre-formed Fibrils, Tag Free is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).

Reinheit: 95 %

Endotoxin-Niveau: 0.05 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries no "tag". () The protein has a calculated MW of 45.8 kDa.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 7.5

Lagerung: -80 °C

Informationen zur Lagerung: -70°C

Antigendetails

Target: tau-441

Hintergrund: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molekulargewicht: 45.8 kDa

NCBI Accession: NP_005901