tau-441 (Pro301Ser-Mutant) protein (His tag)

Produktnummer ABIN7482545

Produktdetails

Target: tau-441

Protein-Typ: Recombinant

Proteineigenschaft: Pro301Ser-Mutant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified)

Sequenz: Met 1 - Leu 441

Produktmerkmale: Human Tau-441 (P301S), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301S).

Reinheit: 90 %

Endotoxin-Niveau: 1.0 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.7 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: tau-441

Hintergrund: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molekulargewicht: 47.7 kDa