tau-441 (Lys18), (Pro301Leu-Mutant) Protein

Produktnummer ABIN7488876

Produktdetails

Target: tau-441

Protein-Typ: Recombinant

Proteineigenschaft: Lys18, Pro301Leu-Mutant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)

Sequenz: Gln 244 - Glu 372

Produktmerkmale: Human Tau-441 (K18, P301L) Protein, Tag Free is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L).

Reinheit: 95 %

Endotoxin-Niveau: 0.1 EU per μg

Güteklasse: HPLC verified

Anwendungsinformationen

Kommentare:

This protein carries no "tag". () The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5

Lagerung: -80 °C

Informationen zur Lagerung: -70°C

Antigendetails

Target: tau-441

Andere Bezeichnung: Tau-441 

Hintergrund: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molekulargewicht: 13.8 kDa