CD24 Protein (His tag)

Produktnummer ABIN7489078

Dieses Recombinant CD24-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CD24 Protein (His tag) (ABIN7489078)

Target: CD24 (CD24 Molecule (CD24))

Protein-Typ: Recombinant

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Reinheit: 90 %

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD24 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus CD24 Protein, His Tag

Sequenz: Thr 27 - Lys 54

Produktmerkmale: Cynomolgus CD24 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Thr 27 - Lys 54 (Accession # I7GKK1-1).

Endotoxin-Niveau: 1.0 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 4.9 kDa. The protein migrates as 25-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: CD24 (CD24 Molecule (CD24))

Andere Bezeichnung: CD24

Hintergrund: CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Molekulargewicht: 4.9 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation