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CD47 Protein (CD47) (Biotin,Fc-Avi Tag)

Recombinant CD47-Protein exprimiert in HEK-293 Cells.
Produktnummer ABIN7482388

Kurzübersicht für CD47 Protein (CD47) (Biotin,Fc-Avi Tag) (ABIN7482388)

Target

Alle CD47 Proteine anzeigen
CD47

Protein-Typ

Recombinant

Spezies

  • 36
  • 14
  • 6
  • 6
  • 4
  • 2
  • 1
Maus

Quelle

  • 41
  • 8
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Reinheit

95 %

Güteklasse

MALS verified
  • Aufreinigungstag / Konjugat

    Dieses CD47 Protein ist gelabelt mit Biotin,Fc-Avi Tag.

    Verwendungszweck

    Biotinylated Mouse CD47 Protein, Fc,Avitag™ (MALS verified)

    Sequenz

    Gln 19 - Lys 140

    Produktmerkmale

    Biotinylated Mouse CD47 Protein, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Lys 140 (Accession # Q61735-1).

    Endotoxin-Niveau

    1.0 EU per μg
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  • Kommentare

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,Fc , Avi) The protein has a calculated MW of 42.0 kDa. The protein migrates as 60-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C
  • Target

    CD47

    Andere Bezeichnung

    CD47

    Hintergrund

    Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

    Molekulargewicht

    42.0 kDa
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