CCR4 Protein-VLP

Produktnummer ABIN7491560

Dieses VLP CCR4-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CCR4 Protein-VLP (ABIN7491560)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Protein-Typ: VLP

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Verwendungszweck: Human CCR4 full length protein-VLP

Produktmerkmale: VLP

Anwendungsinformationen

Kommentare:

Virus-like particles (VLPs) are self-assembling multi-protein nanoparticles with similar structural organization and conformation as viruses but without viral genome. The size of the VLP is about 100-150nm. It is secreted from the surface of the cells that express target membrane proteins (MPs). The purified VLPs have the target MPs inserted in a complete bilayer phospholipid membrane structure, mimic the natural membrane-penetrating state of the protein.
VLPs can be used for routine biochemical analysis, including ELISA, SPR affinity analysis, phage display screenings, protein labeling and cell binding experiments, Flow virometry analysis, etc. It can also be used as functional protein antigens to develop active antibodies with high drug potentials because the target protein on VLP exhibits a state like its native state on the cell surface.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Andere Bezeichnung: CCR4

Hintergrund: The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Molekulargewicht: The human full length CCR4 Protein has a MW of 41.4 kDa

UniProt: P51679