Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CXCR4 Protein

Dieses Synthetic Nanodisc CXCR4-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN7491625

Kurzübersicht für CXCR4 Protein (ABIN7491625)

Target

Alle CXCR4 Proteine anzeigen
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Protein-Typ

Synthetic Nanodisc

Spezies

  • 14
  • 4
  • 2
  • 1
Human

Quelle

  • 9
  • 7
  • 3
HEK-293 Cells
  • Verwendungszweck

    Human CXCR4 full length protein-synthetic nanodisc

    Produktmerkmale

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!
    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 16.256,82 €

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Kommentare

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    Andere Bezeichnung

    CXCR4

    Hintergrund

    A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.

    Molekulargewicht

    The human full length CXCR4 protein has a MW of 39.7 kDa

    UniProt

    P61073

    Pathways

    Regulation of Cell Size, CXCR4-mediated Signaling Events
Sie sind hier:
Chat with us!