CCL28 Protein

Produktnummer ABIN7455692

Dieses Recombinant CCL28-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für CCL28 Protein (ABIN7455692)

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: Greater than 95 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human C-C Motif Chemokine 28 is produced by our E.coli expression system and the target gene encoding Ser20-Tyr127 is expressed.

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Affinity purification

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Andere Bezeichnung: CCL28

Hintergrund: Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83 % sequence identity in their mature regions.

Molekulargewicht: 12.49 KDa

UniProt: Q9NRJ3