Ectodysplasin A Protein (EDA) (Fc Tag)

Produktnummer ABIN7490962

Dieses Recombinant Ectodysplasin A-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Ectodysplasin A Protein (EDA) (Fc Tag) (ABIN7490962)

Target: Ectodysplasin A (EDA)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Ectodysplasin A Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human EDA Protein with N-terminal human Fc tag

Spezifität: HFc (Glu99-Ala330) EDA (Ser160-Ser391)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Ectodysplasin A (EDA)

Andere Bezeichnung: EDA

Hintergrund: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is 55-70 kDa due to glycosylation.

UniProt: Q92838

Pathways: Tube Formation