IgE Protein (AA 1-432) (His tag)

Produktnummer ABIN7490715

Recombinant IgE-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für IgE Protein (AA 1-432) (His tag) (ABIN7490715)

Target: IgE

Protein-Typ: Recombinant

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Applikation: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Produktdetails

Proteineigenschaft: AA 1-432

Aufreinigungstag / Konjugat: Dieses IgE Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Cynomolgus IgHE protein with C-terminal 6xHis tag

Spezifität: IgHE(Ala1-Lys432) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Anwendungsinformationen

Applikationshinweise: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Kommentare:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: IgE

Andere Bezeichnung: IgHE

Hintergrund: Immunoglobulin heavy constant epsilon,IGHE
IGHE (Immunoglobulin Heavy Constant Epsilon) is a Protein Coding gene. Diseases associated with IGHE include Toxocariasis and Latex Allergy. Among its related pathways are Cytokine Signaling in Immune system and RET signaling. Gene Ontology (GO) annotations related to this gene include antigen binding. An important paralog of this gene is IGHG2.

Molekulargewicht: predicted molecular mass of 48.3 kDa after removal of the signal peptide. The apparent molecular mass of cIgHE-His is 55-70 kDa due to glycosylation.