Tspan-8 Protein (His tag)
Kurzübersicht für Tspan-8 Protein (His tag) (ABIN7317005)
Target
Alle Tspan-8 (TSPAN8) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Tspan-8 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Cynomolgus TSPAN8 Protein, His Tag
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Sequenz
- Lys 110 - Ser 205
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Produktmerkmale
- Cynomolgus TSPAN8, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 110 - Ser 205 (Accession # G7PI18-1).
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Endotoxin-Niveau
- 1.0 EU per μg
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Tetraspanin 8 (TSPAN8) (AA 1-237) protein (His tag)
custom-made TSPAN8 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 1-235) protein (His tag)custom-made TSPAN8 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (Fc Tag)TSPAN8 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tetraspanin 8 (TSPAN8) proteinTSPAN8 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (GST tag)TSPAN8 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (GST tag)TSPAN8 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
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Kommentare
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This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 17-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
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Andere Bezeichnung
- TSPAN8
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Hintergrund
- Synonyms:CO-029,tetraspanin 8,TM4SF3,TM4SF3tspan-8,Transmembrane 4 superfamily member 3tetraspanin-8,TSPAN8,Tspan-8,Tumor-associated antigen CO-029,Description:Tspan8 is 1 of the 33 mammalian members of the tetraspanin family, composed of transmembrane proteins that organize laterally, together or with other membrane partners such as integrins, to form 'tetraspanin webs'. These platforms signal within cells to regulate many cellular processes: adhesion, migration, invasion or survival Tspan8 has been implicated in many types of cancer.Overexpression was reported in glioma and colorectal, esophageal, hepatic, gastric and pancreatic carcinoma. Tspan8 exerts a pro-invasive function by controlling cell-cell and cell-matrix interactions through its association with membrane partners such as α6β4 integrin-protein kinase C (PKC)-activated, E-cadherin, EpCAM, claudin-7 and CD44. Moreover, Tspan8 may be a promising new therapeutic target, as Tspan8-specific antibodies were shown to reduce cell motility, block tumor angiogenesis in vivo.
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Molekulargewicht
- 12.7 kDa
Target
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