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CD28 Protein (CD28) (His tag)

Dieses Recombinant CD28-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN7447918

Kurzübersicht für CD28 Protein (CD28) (His tag) (ABIN7447918)

Target

Alle CD28 Proteine anzeigen
CD28

Protein-Typ

Recombinant

Spezies

  • 21
  • 13
  • 9
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Ratte

Quelle

  • 19
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Reinheit

90,00 %
  • Aufreinigungstag / Konjugat

    Dieses CD28 Protein ist gelabelt mit His tag.

    Verwendungszweck

    Rat CD28 Protein, His Tag (BLI verified)

    Sequenz

    Asn 20 - Leu 150

    Produktmerkmale

    Rat CD28, His Tag is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Leu 150 (Accession # P31042-1).

    Endotoxin-Niveau

    1.0 EU per μg
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  • Kommentare

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C
  • Target

    CD28

    Andere Bezeichnung

    CD28

    Hintergrund

    Synonyms:CD28,Tp44,Description:T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

    Molekulargewicht

    16.9 kDa

    NCBI Accession

    NP_037253

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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