CD28 Protein (CD28) (His tag)
Kurzübersicht für CD28 Protein (CD28) (His tag) (ABIN7447918)
Target
Alle CD28 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses CD28 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Rat CD28 Protein, His Tag (BLI verified)
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Sequenz
- Asn 20 - Leu 150
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Produktmerkmale
- Rat CD28, His Tag is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Leu 150 (Accession # P31042-1).
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Endotoxin-Niveau
- 1.0 EU per μg
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Kommentare
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- CD28
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Andere Bezeichnung
- CD28
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Hintergrund
- Synonyms:CD28,Tp44,Description:T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
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Molekulargewicht
- 16.9 kDa
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NCBI Accession
- NP_037253
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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