CD4 Protein (CD4) (Biotin,His-Avi Tag)

Produktnummer ABIN7316799

Recombinant CD4-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)

Target: CD4

Protein-Typ: Recombinant

Spezies: Rhesusaffen

Quelle: HEK-293 Cells

Reinheit: 95,00 %

Güteklasse: MALS verified

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD4 Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)

Sequenz: Lys 26 - Trp 390

Produktmerkmale: Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).

Endotoxin-Niveau: 1.0 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Molekulargewicht: 44.0 kDa

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events