Neuropilin 1 Protein (NRP1) (AA 22-644) (His tag)
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- Target Alle Neuropilin 1 (NRP1) Proteine anzeigen
- Neuropilin 1 (NRP1)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 22-644
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Neuropilin 1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Human Neuropilin-1 Protein
- Sequenz
- Phe22-Lys644
- Produktmerkmale
- Recombinant Human Neuropilin-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe22-Lys644.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human VEGF165, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human Neuropilin-1, His Tag with the EC50 of 2.0μg/ml determined by ELISA. See testing image for detail.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Neuropilin 1 (NRP1)
- Andere Bezeichnung
- Neuropilin-1 (NRP1 Produkte)
- Hintergrund
- Neuropilin 1 (NRP1) is a transmembrane glycoprotein that acts as a co-receptor for a number of extracellular ligands including class III/IV semaphorins, certain isoforms of vascular endothelial growth factor and transforming growth factor beta.
- Molekulargewicht
- 70.97 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001019799
- Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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