NOTCH4 Protein (AA 1042-1441) (His tag)

Produktnummer ABIN7275367

Produktdetails

Target: NOTCH4 (Notch 4 (NOTCH4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1042-1441

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NOTCH4 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse Notch 4 Protein

Sequenz: Glu1042-Leu1441

Produktmerkmale: Recombinant Mouse Notch 4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu1042-Leu1441.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PB, 500 mM NaCl, 10 % Glycerol ( pH 7.0).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: NOTCH4 (Notch 4 (NOTCH4))

Andere Bezeichnung: Notch 4 (NOTCH4 Produkte)

Hintergrund: The Notch signaling pathway is important for cell-cell communication, it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.

Molekulargewicht: 42.91 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

UniProt: P31695

Pathways: Notch Signalweg