MFAP5 Protein (AA 22-173) (Fc Tag)

Produktnummer ABIN7275231

Produktdetails

Target: MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-173

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MFAP5 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human MFAP5 Protein

Sequenz: Ile22-Leu173

Produktmerkmale: Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile22-Leu173.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: MFAP5 (Microfibrillar Associated Protein 5 (MFAP5))

Andere Bezeichnung: MFAP5 (MFAP5 Produkte)

Hintergrund: Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC.

Molekulargewicht: 44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Tris-Bis PAGE result.