LILRB2 Protein (AA 22-457) (Biotin,His-Avi Tag)

Produktnummer ABIN7275188

Recombinant LILRB2-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für LILRB2 Protein (AA 22-457) (Biotin,His-Avi Tag) (ABIN7275188)

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 22-457

Aufreinigungstag / Konjugat: Dieses LILRB2 Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Biotinylated Human LILRB2/CD85d/ILT4 Protein

Sequenz: Gln22-Arg457

Produktmerkmale: Recombinant Biotinylated Human LILRB2/CD85d/ILT4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Arg457.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Immobilized Biotinylated Human LILRB2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-LILRB2 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.,Biotinylated Human LILRB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Biotinylated Human LILRB2 is greater than 95% as determined by SEC-HPLC.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))

Andere Bezeichnung: LILRB2

Hintergrund: The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.

Molekulargewicht: 50.2 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.

Pathways: Cellular Response to Molecule of Bacterial Origin