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Integrin alpha 2 beta 1 (ITGA2 & ITGB1) Heterodimer (AA 30-1132) protein (His tag)

Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275051
  • Target
    Integrin alpha 2 beta 1 (ITGA2 & ITGB1) Heterodimer
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 30-1132
    Spezies
    Human
    Quelle
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    His tag
    Verwendungszweck
    Human Integrin alpha 2 beta 1 (ITGA2 & ITGB1) Heterodimer Protein
    Sequenz
    Tyr30-T1132 (ITGA2) acidic tail & Gln21-Asp728 (ITGB1) basic tail
    Spezifität
    Uni-Prot: P17301-1 (ITGA2), P05556-1 (ITGB1)
    Produktmerkmale
    Recombinant Human Integrin alpha 2 beta 1(ITGA2 & ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr30-T1132(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Integrin alpha 2 beta 1 (ITGA2 & ITGB1) Heterodimer
    Hintergrund
    The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.
    Molekulargewicht
    126.6 kDa(ITGA2)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result.
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