IL-10RA Protein (AA 22-233) (His tag)
-
- Target Alle IL-10RA (IL10RA) Proteine anzeigen
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 22-233
-
Spezies
- Cynomolgus
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL-10RA Protein ist gelabelt mit His tag.
- Verwendungszweck
- Cynomolgus IL-10 R alpha Protein
- Sequenz
- His22-Asn233
- Produktmerkmale
- Recombinant Cynomolgus IL-10 R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Asn233.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-10, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus IL-10 R alpha, His Tag with the EC50 of 8.9ng/ml determined by ELISA. The affinity constant of 0.93 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL10RA Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- Andere Bezeichnung
- IL-10 R alpha (IL10RA Produkte)
- Synonyme
- IL10R1 Protein, IL10RA Protein, CD210 Protein, CD210a Protein, CDW210A Protein, HIL-10R Protein, IL-10R1 Protein, IL10R Protein, AW553859 Protein, CDw210 Protein, CDw210a Protein, Il10r Protein, mIL-10R Protein, interleukin 10 receptor subunit alpha Protein, interleukin 10 receptor, alpha Protein, IL10RA Protein, Il10ra Protein
- Hintergrund
- The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne's disease (JD). JD is a chronic enteritis in cattle caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is responsible for significant economic losses to the dairy industry. Several candidate genes including IL10RA have been found to be associated with JD.
- Molekulargewicht
- 25.34 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WJ66
- Pathways
- Growth Factor Binding
-