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IgE Protein (AA 198-421) (His-Avi Tag)

Dieses Recombinant IgE-Protein wird in HEK-293 Cells exprimiert.
Produktnummer ABIN7274857

Kurzübersicht für IgE Protein (AA 198-421) (His-Avi Tag) (ABIN7274857)

Target

Alle IgE Proteine anzeigen
IgE

Protein-Typ

Recombinant

Spezies

  • 11
  • 6
  • 4
  • 4
  • 2
Maus

Quelle

  • 8
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
HEK-293 Cells

Reinheit

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Proteineigenschaft

    AA 198-421

    Aufreinigungstag / Konjugat

    Dieses IgE Protein ist gelabelt mit His-Avi Tag.

    Verwendungszweck

    Mouse IgE Protein

    Sequenz

    Asp198-Ser421

    Produktmerkmale

    Recombinant Mouse IgE Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp198-Ser421.

    Sterilität

    0.22 μm filtered

    Endotoxin-Niveau

    Less than 1EU per μg by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IgE

    Hintergrund

    Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

    Molekulargewicht

    28.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.

    UniProt

    P06336
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