PF4 Protein (AA 32-101) (Fc Tag)

Produktnummer ABIN7274446

Dieses Recombinant PF4-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für PF4 Protein (AA 32-101) (Fc Tag) (ABIN7274446)

Target: PF4 (Platelet Factor 4 (PF4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 32-101

Aufreinigungstag / Konjugat: Dieses PF4 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human CXCL4 Protein

Sequenz: Glu32-Ser101

Produktmerkmale: Recombinant Human CXCL4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu32-Ser101.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CXCL4, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CXCL4 Antibody, hFc Tag with the EC50 of 6ug/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PF4 (Platelet Factor 4 (PF4))

Andere Bezeichnung: CXCL4

Hintergrund: Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes.

Molekulargewicht: 34.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

UniProt: P02776