SARS-CoV NSP3 Protein (AA 1564-1880) (His tag)

Produktnummer ABIN7274382

Produktdetails

Target: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1564-1880

Spezies: SARS Coronavirus-2 (SARS-CoV-2)

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SARS-CoV NSP3 Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-COV-2 PLpro/papain-like protease Protein

Sequenz: Glu1564-Val1880

Produktmerkmale: Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 100 mM NaCl, 10 % Glycerol ( pH 8.5).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Andere Bezeichnung: PLpro (SARS-CoV NSP3 Produkte)

Substanzklasse: Viral Protein

Hintergrund: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Molekulargewicht: 39.2 kDa same as Tris-Bis PAGE result.

NCBI Accession: YP_009725299