CADM1 Protein (AA 48-388) (His tag)

Produktnummer ABIN7274017

Dieses Recombinant CADM1-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CADM1 Protein (AA 48-388) (His tag) (ABIN7274017)

Target: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Produktdetails

Proteineigenschaft: AA 48-388

Aufreinigungstag / Konjugat: Dieses CADM1 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse CADM1/IGSF4A Protein

Sequenz: Gln48-Asp388

Produktmerkmale: Recombinant Mouse CADM1/IGSF4A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln48-Asp388.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Andere Bezeichnung: CADM1

Hintergrund: The cell adhesion molecule 1 (CADM1) is a molecule of cell adhesion with multiple functions and has been identified as a tumor suppressor gene. CADM1 has multifunctions on the pathogenesis of malignancies, and other normal cells such as immune cells. On the contrary to these cutaneous solid tumors except for Merkel cell carcinoma, cutaneous lymphomas, such as adult-T cell leukemia/lymphoma, mycosis fungoides, and Sézary syndrome, increase their CADM1 expression for the development of tumor environment.

Molekulargewicht: 39.1 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.

UniProt: Q8R5M8-1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation