TNNC1 Protein

Produktnummer ABIN7317698

Dieses Recombinant TNNC1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für TNNC1 Protein (ABIN7317698)

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human Troponin C/TNNC1 Protein

Sequenz: Met 1-Glu161

Produktmerkmale: A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.

Endotoxin-Niveau: Please contact us for more information.

Anwendungsinformationen

Kommentare:

20 kDa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TNNC1 (Cardiac Troponin C (TNNC1))

Andere Bezeichnung: TNNC1

Hintergrund:

Background: Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC

Molekulargewicht: 18.4 kDa

NCBI Accession: NP_003271