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Vinculin Protein (VCL) (His tag)

Dieses Recombinant Vinculin-Protein wird in HEK-293 Cells exprimiert.
Produktnummer ABIN7198696

Kurzübersicht für Vinculin Protein (VCL) (His tag) (ABIN7198696)

Target

Alle Vinculin (VCL) Proteine anzeigen
Vinculin (VCL)

Protein-Typ

Recombinant

Spezies

  • 12
  • 1
Maus

Quelle

  • 10
  • 2
  • 1
HEK-293 Cells

Reinheit

> 90 % as determined by SDS-PAGE
  • Aufreinigungstag / Konjugat

    Dieses Vinculin Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Mouse VCL/Vinculin Protein (His Tag)

    Sequenz

    Met1-Gln1066

    Produktmerkmale

    A DNA sequence encoding the mouse VCL (NP_033528.3) (Met1-Gln1066) was expressed with a C-terminal polyhistidine tag.

    Endotoxin-Niveau

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from sterile PBS, pH 7.4

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Vinculin (VCL)

    Andere Bezeichnung

    VCL/Vinculin

    Hintergrund

    Background: Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.

    Synonym: 9430097D22,AA571387,AI462105,AW545629

    Molekulargewicht

    118.2 kDa

    NCBI Accession

    NP_033528

    Pathways

    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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