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UPB1 Protein (His tag)

UPB1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319223
  • Target Alle UPB1 Proteine anzeigen
    UPB1 (Ureidopropionase, beta (UPB1))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 2
    Human
    Quelle
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses UPB1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human BUP1 Protein (His Tag)
    Sequenz
    Met 1-Glu384
    Produktmerkmale
    Recombinant Human beta-Ureidopropionase is produced by our E.coli expression system and the target gene encoding Met1-Glu384 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product UPB1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    UPB1 (Ureidopropionase, beta (UPB1))
    Andere Bezeichnung
    BUP1 (UPB1 Produkte)
    Synonyme
    MGC82230 Protein, wu:fb69e03 Protein, zgc:64020 Protein, BUP1 Protein, AI195023 Protein, Bup1 Protein, ureidopropionase, beta S homeolog Protein, beta-ureidopropionase 1 Protein, ureidopropionase, beta Protein, UreidoPropionase Beta Protein, upb1.S Protein, UPB1 Protein, upb1 Protein, upb-1 Protein, Upb1 Protein
    Hintergrund

    Background: β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid, respectively. Defects in β-Ureidopropionase are the cause of β-Ureidopropionase deficiency that is characterized by muscular hypotonia, dystonic movements, scoliosis, microcephaly and severe developmental delay.

    Synonym: Beta-Ureidopropionase, BUP-1, Beta-Alanine Synthase, N-Carbamoyl-Beta-Alanine Amidohydrolase, UPB1, BUP1

    Molekulargewicht
    44.2 kDa
    UniProt
    Q9UBR1
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