TWF1 Protein
Quick Overview for TWF1 Protein (ABIN7317476)
Target
Alle TWF1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Human TWF1/Twinfilin-1 Protein
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Sequenz
- Met 1-Asp 252
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Produktmerkmale
- A DNA sequence encoding the human TWF1 isoform 4 (Q12792-4) (Met 1-Asp 252) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4, 10 % glycerol
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))
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Andere Bezeichnung
- TWF1/Twinfilin-1
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Hintergrund
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Background: Twinfilin-1; also known as Protein A6; Protein tyrosine kinase 9; TWF1 and PTK9; is a cytoplasm protein which belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1; a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is expressed at high levels in the colon; testis; ovary; prostate and lung. It is expressed at lower levels in the brain; bladder and heart. It is not detected in liver. TWF1 / PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization; likely by sequestering G-actin. By capping the barbed ends of filaments; it also regulates motility. TWF1 / PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Synonym: A6;MGC23788;MGC41876;PTK9
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Molekulargewicht
- 29 kDa
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Pathways
- Regulation of Actin Filament Polymerization, Maintenance of Protein Location
Target
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