TPM3 Protein

Produktnummer ABIN7319117

Recombinant TPM3-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für TPM3 Protein (ABIN7319117)

Target: TPM3 (Tropomyosin 3 (TPM3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human Tropomyosin α-3 Chain/TPM3 Protein

Sequenz: Met 1-Met248

Produktmerkmale: Recombinant Human Tropomyosin alpha-3 Chain is produced by our E.coli expression system and the target gene encoding Met1-Met248 is expressed.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: TPM3 (Tropomyosin 3 (TPM3))

Andere Bezeichnung: Tropomyosin alpha-3 Chain/TPM3

Hintergrund:

Background: Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.

Synonym: Tropomyosin Alpha-3 Chain, Gamma-Tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3

Molekulargewicht: 29.0 kDa