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TPBG Protein (mFc Tag)

Dieses Recombinant TPBG-Protein wird in Human Cells exprimiert.
Produktnummer ABIN7319827

Kurzübersicht für TPBG Protein (mFc Tag) (ABIN7319827)

Target

Alle TPBG Proteine anzeigen
TPBG (Trophoblast Glycoprotein (TPBG))

Protein-Typ

Recombinant

Spezies

  • 23
  • 3
  • 3
  • 2
  • 1
Human

Quelle

  • 22
  • 3
  • 2
  • 2
  • 1
  • 1
Human Cells

Reinheit

>95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses TPBG Protein ist gelabelt mit mFc Tag.

    Verwendungszweck

    Recombinant Human TPBG/5T4 (C-mFc)

    Sequenz

    Ser32-Ser355

    Produktmerkmale

    Recombinant Human Trophoblast glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a mFc tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    TPBG (Trophoblast Glycoprotein (TPBG))

    Andere Bezeichnung

    TPBG/5T4

    Hintergrund

    Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

    Synonym: 5T4 , 5T4AG, M6P1, WAIF1

    Molekulargewicht

    61.7 kDa

    UniProt

    Q13641
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