TLK2 Protein
Kurzübersicht für TLK2 Protein (ABIN7317071)
Target
Alle TLK2 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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                                            Verwendungszweck
- Recombinant Human TLK2/PKU-ALPHA Protein
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                                            Sequenz
- Leu 397-Asn772
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                                            Produktmerkmale
- A DNA sequence encoding the human TLK2 (Q86UE8-1) (Leu397-Asn772) was fused with two additional amino acids (Gly & Pro) at the N-terminus.
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                                            Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
 
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    Möchten Sie weitere Optionen für dieses Protein ?!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 13.711,36 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 18.117,43 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Frozen, Liquid
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                                            Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10 % glycerol, pH 8.0
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 
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    - TLK2 (Tousled-Like Kinase 2 (TLK2))
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                                            Andere Bezeichnung
- TLK2/PKU-ALPHA
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                                            Hintergrund
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                        Background: Serine / threonine-protein kinase tousled-like 2; also known as PKU-alpha; Tousled-like kinase 2 and TLK2; is a nucleus protein which belongs to the protein kinase superfamily and Ser/Thr protein kinase family. The tousled-like kinases are an evolutionarily conserved family of proteins implicated in DNA repair; DNA replication and mitosis in metazoans and plants. Their absence from the yeasts and other eukaryotic 'microbes' suggests a specific role for them in the development of multicellular organisms. Tousled-like kinase 2 / TLK2 is widely expressed. It is present in fetal placenta; liver; kidney; pancreas; heart and skeletal muscle. It is also found in adult cell lines. Tousled-like kinase 2 / TLK2 contains one protein kinase domain. Tousled-like kinase 2 / TLK2 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Synonym: HsHPK;PKU-ALPHA 
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                                            Molekulargewicht
- 43.6 kDa
 Target
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