TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST)

Produktnummer ABIN7317073

Recombinant TAO Kinase 3-Protein exprimiert in Baculovirus infected Insect Cells.

Kurzübersicht für TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST) (ABIN7317073)

Target: TAO Kinase 3 (TAOK3)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 92 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-411

Aufreinigungstag / Konjugat: Dieses TAO Kinase 3 Protein ist gelabelt mit His-GST.

Verwendungszweck: Recombinant Human TAOK3/JIK/MAP3K18 Protein (aa 1-411, His & GST Tag)

Sequenz: Met 1-Asp 411

Produktmerkmale: A DNA sequence encoding the amino acids (Met 1-Asp 411) of human TAOK3 (Q9H2K8-1) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 3 mM GSH, pH 7.4, 10 % glycerol

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: TAO Kinase 3 (TAOK3)

Andere Bezeichnung: TAOK3/JIK/MAP3K18

Hintergrund: DPK,JIK,MAP3K18,Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to theprotein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains oneprotein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.

Molekulargewicht:

Calculated MW: 74.3 kDa

Observed MW: 85 kDa

Gen-ID: 51347

UniProt: Q9H2K8