SENP7 Protein (AA 695-864)

Produktnummer ABIN7319010

Dieses Recombinant SENP7-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für SENP7 Protein (AA 695-864) (ABIN7319010)

Target: SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 695-864

Verwendungszweck: Recombinant Human SENP7 Protein

Sequenz: Met695-Ala864

Produktmerkmale: Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed with a 6His tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 5 % Glycerol, pH 7.4.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))

Andere Bezeichnung: SENP7

Hintergrund: KIAA1707,SENP7,SSP2,SUMO-1-Specific Protease 2,SUSP2,Sentrin-Specific Protease 7,Sentrin/SUMO-Specific Protease SENP7,Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.

Molekulargewicht:

Calculated MW: 19.8 kDa

Observed MW: 22 kDa

Gen-ID: 57337

UniProt: Q9BQF6