SHPK Protein (His tag)

Produktnummer ABIN7318998

Recombinant SHPK-Protein exprimiert in Human Cells.

Kurzübersicht für SHPK Protein (His tag) (ABIN7318998)

Target: SHPK (Sedoheptulokinase (SHPK))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses SHPK Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Sedoheptulokinase/SHPK Protein (His Tag)

Sequenz: Met 1-Ser478

Produktmerkmale: Recombinant Human Sedoheptulokinase is produced by our Mammalian expression system and the target gene encoding Met1-Ser478 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: SHPK (Sedoheptulokinase (SHPK))

Andere Bezeichnung: Sedoheptulokinase/SHPK

Hintergrund:

Background: Sedoheptulokinase (SHPK) belongs to the FGGY kinase family, and is mainly located in cytoplasm. SHPK is strongly expressed in liver, kidney and pancreas. It is expressed at lower levels in placenta and heart, and very weakly expressed in lung and brain. SHPK catalyzes the chemical reaction: ATP + sedoheptulose = ADP + sedoheptulose 7-phosphatecan, It can transform sedoheptulose to sedoheptulose 7-phosphate in the condition of ATP, and acts as a modulator of macrophage activation through control of glucose metabolism. In addition, It also can be down-regulated by LPS.

Synonym: Sedoheptulokinase,SHK,Carbohydrate kinase-like protein,SHPK,CARKL

Molekulargewicht: 52.5 kDa

UniProt: Q9UHJ6

Pathways: Cellular Response to Molecule of Bacterial Origin