SCGB3A2 Protein

Produktnummer ABIN7319165

Produktdetails

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Recombinant Human UGRP1 Protein

Sequenz: Phe22-Val93

Produktmerkmale: Recombinant Human Uteroglobin-Related Protein 1 is produced by our E.coli expression system and the target gene encoding Phe22-Val93 is expressed.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Andere Bezeichnung: UGRP1 (SCGB3A2 Produkte)

Synonyme: SCGB3A2 Protein, LU103 Protein, PNSP1 Protein, UGRP1 Protein, pnSP-1 Protein, LuLeu1 Protein, Pnsp1 Protein, Utgrp1 Protein, secretoglobin family 3A member 2 Protein, secretoglobin, family 3A, member 2 Protein, SCGB3A2 Protein, Scgb3a2 Protein

Hintergrund:

Background: Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.

Synonym: Secretoglobin Family 3A Member 2, Pneumo Secretory Protein 1, PnSP-1, Uteroglobin-Related Protein 1, SCGB3A2, PNSP1, UGRP1

Molekulargewicht: 7.9 kDa

UniProt: Q96PL1