S100A16 Protein (AA 1-103)

Produktnummer ABIN7319484

Recombinant S100A16-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für S100A16 Protein (AA 1-103) (ABIN7319484)

Target: S100A16 (S100 Calcium Binding Protein A16 (S100A16))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 1-103

Verwendungszweck: Recombinant Human S100A16/S100F Protein

Sequenz: Met1-Ser103

Produktmerkmale: Recombinant Human S100A16 is produced by our E.coli expression system and the target gene encoding Met1-Ser103 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Histidine-HCl, 6 % Trehalose, 4 % Mannitol, 100 mM NaCl, 0.05 % Tween 80, pH 5.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: S100A16 (S100 Calcium Binding Protein A16 (S100A16))

Andere Bezeichnung: S100A16/S100F

Hintergrund: Activating NK Receptor,CD352,KALI,Ly108,NK-T-B-Antigen,NTB-A,NTBA,SF2000,SLAM Family Member 6,SLAMF6,S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-handmotifs. S100 proteins are cell-and tissue-specific and are involved in many intra-and extracellular processes hrough interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and insolution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppress or protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsivegenes, respectively. S100A16 protein is a novel adipogenesis-promoting factor.

Molekulargewicht:

Calculated MW: 11.8 kDa

Observed MW: 12 kDa

Gen-ID: 140576

UniProt: Q96FQ6

Pathways: S100 Proteine