RBP4 Protein (AA 19-201)

Produktnummer ABIN7319379

Recombinant RBP4-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für RBP4 Protein (AA 19-201) (ABIN7319379)

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 19-201

Verwendungszweck: Recombinant Human RBP4 Protein

Sequenz: Glu19-Leu201

Produktmerkmale: Recombinant Human Retinol-Binding Protein 4 is produced by our E.coli expression system and the target gene encoding Glu19-Leu201 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 10 mM CaCl₂, 150 mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Andere Bezeichnung: RBP4

Hintergrund: PRBP,Plasma Retinol-Binding Protein,RBP,RBP4,RDCCAS,Retinol-Binding Protein 4,Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.

Molekulargewicht:

Calculated MW: 21.2 kDa

Observed MW: 20 kDa

NCBI Accession: NP_006735

Pathways: Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response