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Resistin Protein (RETN) (His tag)

Recombinant Resistin-Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN7319264

Kurzübersicht für Resistin Protein (RETN) (His tag) (ABIN7319264)

Target

Alle Resistin (RETN) Proteine anzeigen
Resistin (RETN)

Protein-Typ

Recombinant

Spezies

  • 18
  • 7
  • 4
  • 3
  • 1
Human

Quelle

  • 19
  • 8
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses Resistin Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Human Resistin Protein (His Tag)

    Sequenz

    Lys19-Pro108

    Produktmerkmale

    Recombinant Human Adipose tissue-specific secretory factor is produced by our E.coli expression system and the target gene encoding Lys19-Pro108 is expressed with a 6His tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Acetic acid, pH 3.0.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Resistin (RETN)

    Andere Bezeichnung

    Resistin

    Hintergrund

    Background: Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa, the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

    Synonym: Resistin, Adipose tissue-specific secretory factor, Cysteine-rich secreted protein FIZZ3, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, FIZZ3, HXCP1, RSTN, RETN,ADSF,FIZZ3,RETN1,XCP1

    Molekulargewicht

    10.6 kDa

    NCBI Accession

    NP_065148

    Pathways

    Feeding Behaviour, Smooth Muscle Cell Migration
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