PRM2 Protein (His tag)

Produktnummer ABIN7318947

Dieses Recombinant PRM2-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für PRM2 Protein (His tag) (ABIN7318947)

Target: PRM2 (Protamine 2 (PRM2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PRM2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Protamine-2/PRM2 Protein (His Tag)

Sequenz: Met 1-Phe389

Produktmerkmale: Recombinant Human Ribonucleotide Reductase Small Chain is produced by our Mammalian expression system and the target gene encoding Met1-Phe389 is expressed with a 6His tag at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 5 % Trehalose, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PRM2 (Protamine 2 (PRM2))

Andere Bezeichnung: Protamine-2/PRM2

Hintergrund: RR2,RRM2,Ribonucleoside-Diphosphate Reductase Subunit M2,Ribonucleotide Reductase Small Chain,Ribonucleotide Reductase Small Subunit,Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.

Molekulargewicht:

Calculated MW: 45.9 kDa

Observed MW: 47 kDa

Gen-ID: 6241

UniProt: P31350