Prosaposin Protein (PSAP) (His tag)

Produktnummer ABIN7317152

Recombinant Prosaposin-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für Prosaposin Protein (PSAP) (His tag) (ABIN7317152)

Target: Prosaposin (PSAP)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > (79.8+19.7) % as determined by reducing SDS-PAGE..

Produktdetails

Aufreinigungstag / Konjugat: Dieses Prosaposin Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PSAP/Prosaposin Protein (His Tag)

Sequenz: Met 1-Asn524

Produktmerkmale: A DNA sequence encoding the human PSAP (NP_002769.1) (Met1-Asn524) was expressed with a polyhistidine tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Prosaposin (PSAP)

Andere Bezeichnung: PSAP/Prosaposin

Hintergrund:

Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonym: GLBA,SAP1

Molekulargewicht: 57.9 kDa

NCBI Accession: NP_002769

Pathways: Positive Regulation of Endopeptidase Activity