PRCP Protein (His tag)

Produktnummer ABIN7318751

Dieses Recombinant PRCP-Protein wird in Human Cells produziert.

Kurzübersicht für PRCP Protein (His tag) (ABIN7318751)

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PRCP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PRCP Protein (His Tag)

Sequenz: Leu22-His496

Produktmerkmale: Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc,150 mM NaCl,10 % Glycerol, pH 4.5.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Andere Bezeichnung: PRCP

Hintergrund:

Background: Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH , but enzymatic activity is retained with some substrates at neutral pH . PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.

Synonym: Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP

Molekulargewicht: 54.5 kDa

UniProt: P42785