PDGF-AA Homodimer protein (His tag)

Produktnummer ABIN7318911

Dieses Recombinant PDGF-AA Homodimer-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für PDGF-AA Homodimer protein (His tag) (ABIN7318911)

Target: PDGF-AA Homodimer

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: His tag

Verwendungszweck: Recombinant Human PDGF-AA Protein (His Tag)

Sequenz: Ser87-Thr 211

Produktmerkmale: Recombinant Human Platelet-derived growth factor AA is produced by our E.coli expression system and the target gene encoding Ser87-Thr211 is expressed with a 6His tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PDGF-AA Homodimer

Andere Bezeichnung: PDGF-AA

Hintergrund: PDGF subunit A,PDGF-1,PDGF1,PDGFA,Platelet-derived growth factor A chain,Platelet-derived growth factor alpha polypeptide,Platelet-derived growth factor subunit A,Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. It plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFA is required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis, normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. It plays an important role in wound healing, Signaling is modulated by the formation of heterodimers with PDGFB.

Molekulargewicht:

Calculated MW: 15.9 kDa

Observed MW: 16 kDa

Gen-ID: 5154

UniProt: P04085