PMM2 Protein (His tag)

Produktnummer ABIN7318900

Recombinant PMM2-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für PMM2 Protein (His tag) (ABIN7318900)

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PMM2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PMM2 Protein (His Tag)

Sequenz: Met 1-Ser246

Produktmerkmale: Recombinant Human Phosphomannomutase 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser246 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Andere Bezeichnung: PMM2

Hintergrund:

Background: Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.

Synonym: Phosphomannomutase 2, PMM 2, PMM2

Molekulargewicht: 29.1 kDa

UniProt: O15305