PMM1 Protein (His tag)

Produktnummer ABIN7318899

Dieses Recombinant PMM1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für PMM1 Protein (His tag) (ABIN7318899)

Target: PMM1 (Phosphomannomutase 1 (PMM1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PMM1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PMM1 Protein (His Tag)

Sequenz: Met 1-Ala262

Produktmerkmale: Recombinant Human Phosphomannomutase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala262 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: PMM1 (Phosphomannomutase 1 (PMM1))

Andere Bezeichnung: PMM1

Hintergrund:

Background: Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.

Synonym: Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22

Molekulargewicht: 30.8 kDa

UniProt: Q92871