PON3 Protein (His tag)

Produktnummer ABIN7317316

Dieses Recombinant PON3-Protein wird in Baculovirus infected Insect Cells produziert.

Kurzübersicht für PON3 Protein (His tag) (ABIN7317316)

Target: PON3 (Paraoxonase 3 (PON3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PON3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PON3/Paraoxonase 3 Protein (50 Ser/Asn, His Tag)

Sequenz: Met 1-Leu 354

Produktmerkmale: A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 1 mM CaCL2, 10 % glycerol, 0.1 % DDM

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PON3 (Paraoxonase 3 (PON3))

Andere Bezeichnung: PON3/Paraoxonase 3

Hintergrund:

Background: KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

Synonym: PON3

Molekulargewicht: 42 kDa

Pathways: Monocarboxylic Acid Catabolic Process