NCF2 Protein

Produktnummer ABIN7317174

Dieses Recombinant NCF2-Protein wird in Baculovirus infected Insect Cells produziert.

Kurzübersicht für NCF2 Protein (ABIN7317174)

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Reinheit: > 85 % as determined by reducing SDS-PAGE.

Produktdetails

Verwendungszweck: Recombinant Human NCF2/P67phox Protein

Sequenz: Met 1-Val526

Produktmerkmale: A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 300 mM NaCl, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))

Andere Bezeichnung: NCF2/P67phox

Hintergrund: NCF-2,NOXA2,P67-PHOX,P67PHOX,NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

Molekulargewicht:

Calculated MW: 59.9 kDa

Observed MW: 60 kDa

Gen-ID: 4688

UniProt: P19878